Publications
34. Reaction Screening in Multiwell Plates: High-Throughput Optimization of a Buchwald-Hartwig Amination
Cook, A.; Clément, R.; Newman, S. G. Nature Prot. 2021, in press.
33. Exhaustive Reduction of Esters Enabled by Nickel Catalysis
Prakash, S.; Cook, A.; Zheng, Y.-Z.; Newman, S. G. J. Am. Chem. Soc. 2020, 142, 8109.
DOI: 10.1021/jacs.0c02405
Highlighted in ChemistryViews
32. Reaction Cycling for Kinetic Analysis in Flow
Sullivan, R. J.; Newman, S. G. J. Org. Chem. 2020, 85, 5464.
Highlighted in OPRD
31. Exploring Homogeneous Conditions for Mild Buchwald-Hartwig Amination in Batch and Flow
Kashani, S. K.; Jessiman, J. E.; Newman, S. G. Org. Process Res. Devel. 2020, 24, 1948.
Invited contribution for flow chemistry special issue
30. Nickel-Catalyzed Domino Heck-Type Reactions using Methyl Esters as Cross-Coupling Electrophiles
Zheng, Y.-L.; Newman, S. G. Angew. Chem. Int. Ed. 2019, 58, 18159.
29. Overcoming Scope Limitations in Cross-Coupling of Diazo Nucleophiles by Manipulating Catalyst Speciation and Using Flow Diazo Generation
Sullivan, R. J.; Freure, G. P. R.; Newman, S. G. ACS Catal. 2019, 9, 5263.
28. Ketone Synthesis by a Nickel-Catalyzed Dehydrogenative Cross-Coupling of Primary Alcohols
Verheyen, T.; Turnhout, L. v.; Vandavasi, J. K.; De Borggraeve, W. M.; Isbrandt, E. S.; Newman, S. G. J. Am. Chem. Soc. 2019, 141, 6869.
DOI: 10.1021/jacs.9b03280
27. Methyl Esters as Cross-Coupling Electrophiles: Direct Synthesis of Amide Bonds
Zheng, Y.-L.; Newman, S. G. ACS Catal. 2019, 9, 4426.
26. High Throughput Strategies for the Discovery and Optimization of Catalytic Reactions
Isbrandt, E. S.; Sullivan, R. J.; Newman, S. G. Angew. Chem. Int. Ed. 2019, 58, 7180.
25. Nickel-Catalyzed Amide Bond Formation from Methyl Esters
Ben Halima, T.; Masson-Makdissi, J.; Newman, S. G. Angew. Chem. Int. Ed. 2018, 57, 12925.
24. Flow-Assisted Synthesis of Heterocycles at High Temperatures
Sullivan, J.; Newman, S. in Flow Chemistry for the Synthesis of Heterocycles. K. Sharma & E. Van der Eycken, Eds. Springer 2018.
DOI: 10.1007/7081_2018_18
23. Switchable Selectivity in the Pd-Catalyzed Alkylative Cross-Coupling of Esters
Masson-Makdissi, J.; Vandavasi, J. K.; Newman, S. G. Org. Lett. 2018, 20, 4094.
DOI: 10.1021/acs.orglett.8b01646
22. A High-Throughput Approach to Discovery: Heck-Type Reactivity with Aldehydes
Vandavasi, J. K.; Newman, S. G. Synlett. 2018, 29, 2081.
Invited Synpacts article
Highlighted in OPRD
21. Overcoming Solid Handling Issues in Continuous Flow Substitution Reactions through Ionic Liquid Formation
Kashani, S. K.; Sullivan, R. J.; Andersen, M.; Newman, S. G. Green Chem. 2018, 20, 1748.
DOI: 10.1039/C8GC00618K
20. Chiral Auxiliary Recycling in Continuous Flow: Automated Recovery and Reuse of Oppolzer’s Sultam
Sullivan, R. J.; Newman, S. G. Chem. Sci. 2018, 9, 2130.
DOI: 10.1039/C7SC05192A
Highlighted in OPRD
19. A Nickel-Catalyzed Carbonyl-Heck Reaction
Vandavasi, J. K.; Hua, X.; Ben Halima, H.; Newman, S. G. Angew. Chem. Int. Ed. 2017, 56, 15441.
18. Catalytic Deuteration of Aldehydes with D2O
Isbrandt, E. S.; Vandavasi, J. K.; Zhang, W.; Jamshidi, M. P.; Newman, S. G. Synlett 2017, 28, 2851.
Invited contribution in honor of Prof. Snieckus
17. A Cross-Coupling Approach to Amide Bond Formation from Esters
Ben Halima, T.; Vanadavasi, J. K.; Shkoor, M.; Newman, S. G. ACS Catalysis 2017, 7, 2176.
16. Palladium-Catalyzed Suzuki-Miyaura Coupling of Aryl Esters
Ben Halima, T.; Zhang, W.; Yalaoui, I.; Hong, X.; Yang, Y.-F.; Houk, K. N.; Newman, S. G. J. Am. Chem. Soc. 2017, 139, 1311.
DOI: 10.1021/jacs.6b12329
Highlighted in Synfacts
Highlighted in Organic Chemistry Frontiers
15. Inherent Vs Apparent Chemoselectivity in the Kumada-Corriu Cross-Coupling Reaction
Hua, X.; Masson-Makdissi, J.; Sullivan, R. J.; Newman, S. G. Org. Lett. 2016, 18, 5312.
DOI: 10.1021/acs.orglett.6b02631
Highlighted in Synfacts
14. Continuous Thermal Oxidation of Alkenes with Nitrous Oxide in a Packed Bed Reactor
Newman, S. G.; Lee, K.; Cai, J.; Yang, L.; Green, W. H.; Jensen, K. F. Ind. Eng. Chem. Res. 2015, 54, 4166.
DOI: 10.1039/C3GC41942H
13. Pd(0)-Catalyzed Carboiodination: Early Developments and Recent Advances
Petrone, D. A.; Le, C. M.; Newman, S. G.; Lautens, M. RSC Catalysis Series 21. New Trends in Cross-Coupling: Theory and Applications. 2014, 276.
DOI: 10.1039/9781782620259-00276
12. Tools for Chemical Synthesis in Microsystems
Jensen, K. F.; Reizman, B. J.; Newman, S. G. Lab Chip 2014, 14, 3206.
DOI: 10.1039/C3GC41942H
11. Rapid Wolff–Kishner Reductions in a Silicon Carbide Microreactor
Newman, S. G.; Gu, L.; Lesniak, C.; Victor, G.; Meschke, F.; Abahmane, L.; Jensen, K. F. Green Chem. 2014, 16, 176.
DOI: 10.1039/C3GC41942H
10. The Role of Flow in Green Chemistry and Engineering
Newman, S. G.; Jensen, K. F. Green Chem. 2013, 15, 1456.
DOI: 10.1039/C3GC40374B
9. Enantioselective Rh-Catalyzed Domino Transformations of Alkynylcyclohexadienones with Organoboron Reagents
Keilitz, J.; Newman, S. G.; Lautens, M. Enantioselective Rh-Catalyzed Domino Transformations of Alkynylcyclohexadienones with Organoboron Reagents. Org. Lett. 2013, 15, 1148.
DOI: 10.1021/ol400363f
8. Theoretical Study of Pd(0)-Catalyzed Carbohalogenation of Alkenes: Mechanism and Origins of Reactivities and Selectivities in Alkyl Halide Reductive Elimination from Pd(II) Species
Lan, Y.; Liu, P.; Newman, S. G.; Lautens, M.; Houk, K. N. Chem. Sci. 2012, 3, 1987.
DOI: 10.1039/C2SC20103H
7. Palladium-Catalyzed Carbohalogenation: Bromide to Iodide Exchange and Domino Processes
Newman, S. G.; Howell, J. M.; Nicolaus, N.; Lautens, J. Am. Chem. Soc. 2011, 133, 14916.
DOI: 10.1021/ja206099t
6. Palladium-Catalyzed Carboiodination of Alkenes: Carbon-Carbon Bond Formation with Retention of Reactive Functionality
Newman, S. G.; Lautens, M. J. Am. Chem. Soc. 2011, 133, 1778.
DOI: 10.1021/ja110377q
5. The Use of Bromotrichloromethane in Chlorination Reactions
Newman, S. G.; Bryan, C. S.; Perez, D.; Lautens, M. Synthesis 2011, 342.
4. The Role of Reversible Oxidative Addition in Selective Palladium(0)-Catalyzed Intramolecular
Cross-Couplings of Polyhalogenated Substrates: Synthesis of Brominated Indoles
Newman, S. G.; Lautens, M. J. Am. Chem. Soc. 2010, 132, 11416.
DOI: 10.1021/ja1052335
3. Intramolecular Cross-Coupling of gem-Dibromoolefins: a Mild Approach to 2-Bromo Benzofused Heterocycles
Newman, S. G.; Aureggi, V.; Bryan, C. S.; Lautens, M. Chem. Commun. 2009, 5236.
DOI: 10.1039/B912093A
2. Boron-Catalyzed Direct Aldol Reactions of Pyruvic Acids
Lee, D.; Newman, S. G.; Taylor, M.S. Org. Lett. 2009, 11, 5486.
DOI: 10.1021/ol902322r
1. Factors Controlling Extremely Strong AAA-DDD Triply Hydrogen-Bonded Complexes
Newman, S. G.; Taylor, A.; Boyd, R. J. Chem. Phys. Lett. 2008, 450, 210.